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The POSTBiotic Secret To Gut Health

Gut health is a hot topic these days and for good reason. Statistics show that gastrointestinal issues are common for many people.

According to a survey of more than 71,000 Americans, approximately 61% reported having at least one gastrointestinal symptom during the past week. The most common symptoms included bloating, heartburn, diarrhea, constipation, and abdominal pain.1

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This is perhaps not surprising as digestion is a complex process tasked with digesting food, absorbing nutrients, excreting waste, and more. The mouth, esophagus, stomach, small and large intestines are all involved in this process, as is your liver, gallbladder and pancreas.

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What Is Gut Microbiome And Why Is It Important?

A healthy digestive system depends upon the estimated 200 trillion bacteria and other microbes -- collectively called the gut microbiome -- that live in your gastrointestinal tract. These microbiota help break down food, aid in digestion and nutrient absorption, produce certain vitamins and amino acids, and even support the immune system.2, 3So if you have unpleasant digestive symptoms, it’s likely caused by an imbalance of your microbiome.  

What Happens If Gut Microorganisms Are Imbalanced?

The gut microbiome relies upon a precise balance of good and bad microorganisms to do its job properly. If an imbalance occurs -- i.e. bad bacteria outnumbers good bacteria -- digestive issues can occur. It can even lead to many different health conditions and diseases, including:4a

  • Inflammatory bowel disease
  • Irritable bowel syndrome
  • Atherosclerosis
  • Hypertension
  • Heart disease
  • Chronic kidney disease
  • Obesity
  • Type 2 diabetes
  • And more

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What Is A Probiotic And What Does It Do?

Probiotics are popular these days due to reported gut health benefits. Indeed, studies that suggested a link between gut bacteria and overall health is what triggered an emphasis on probiotics. But what exactly is a probiotic?

Probiotics are good bacteria that live in your gut. You can increase the good bacteria in your digestive  tract by taking probiotic supplements or by eating probiotic foods, such as sauerkraut and yogurt. Though beneficial for your health, probiotics don't stay in your gut long-term; therefore, they must be continually replenished. 

In addition, probiotics need food to survive. That's where prebiotics come in. 

probiotics and postbiotics

The Importance of Prebiotics

For probiotics to grow and thrive, they must have a continual food source of prebiotics commonly known as dietary fiber. Fiber plays a huge role in digestive health as well as overall health. 

It works like this...

When you eat food, it enters your stomach to be mixed with gastric juices and predigested, giving it the consistency of oatmeal. This partially digested food  known as chyme is then moved to your small intestine.

Enzymes in the small intestine break down molecules in foods. The small intestine then absorbs their nutrients -- i.e. vitamins, minerals, carbohydrates, etc. -- and fluids.

After it completes the main digestive process, the small intestine sends fiber and other remaining foods to the large intestine (colon). Because insoluble fiber is a type of resistant starch that cannot be broken down by digestive enzymes, the colon uses it to help form stool.  This fiber is excreted from the digestive system relatively intact. 

Soluble fiber, however, is broken down by beneficial bacteria in the large intestine. This bacteria digests (ferments) it and then excretes postbiotic metabolites.

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Postbiotic Metabolites For A Healthy Gut and Body

Bacterial fermentation of fiber produces many different types of postbiotic metabolites, including:4b, 4c

 

  • Vitamin K, essential for proper blood clotting 
  • B-vitamin synthesis, helping to create all B-vitamins
  • Hydrogen peroxide that inhibits the growth of candida and other yeasts
  • Antimicrobial peptides (AMPs) that support immune function by suppressing the growth of harmful gut bacteria. 
  • Short-chain fatty acids (acetic, propionic and butyric acid) that support immunity. They also promote a healthy gut by spurring the growth of beneficial bacteria while suppressing growth of the bad kind. 

As you can see, postbiotics can potentially promote health in many ways. In fact, researchers believe they may provide most of the health benefits usually attributed to fiber and probiotics.  Isn't this reason enough to increase the production of postbiotics? But...how do you do that?

The way to increase health-supporting postbiotics is to increase beneficial bacteria in your gut. 

How Can I Increase Good Bacteria In My Gut?

There are 4 main ways to increase good bacteria in your gut.

postbiotics foods

Eat more foods that contain probiotics (or take supplements) 

Fermented foods are rich sources of probiotics, and probiotic supplements contain various strains of good bacteria, typically Lactobacilliand Bifidobacteria. Fermented foods include sauerkraut, yogurt, and kombucha. Please note: though yogurt is a popular probiotic food, not all brands are probiotic. Before purchasing yogurt for probiotic purposes, make sure it contains "live active cultures." (It should say this on the label.)

Eat fibrous foods (prebiotics) 

The recommended daily fiber intake for adults is around 25 grams for females and 38 grams for males.5(Research shows that most Americans get less than half that amount.) However, the problem with eating large amounts of fiber foods is that it often creates gas, bloating, and stomach pains...the very digestive issues that you may be trying to heal. More about that in a minute.

Avoid foods and activities that kill gut bacteria

Certain foods kill probiotics (good bacteria) and/or feed bad bacteria. To increase good bacteria in your gut, try to avoid foods with added sugar, refined carbohydrates, and heavily processed foods. Also, go easy on alcoholic beverages. Reducing stress and getting regular exercise is another way to maintain a balanced gut microbiome.

harmful to probiotics list

Take a good daily POSTBiotic supplement

The BEST POSTBiotics are the short-chain fatty acid metabolites, especially butyrate.

Benefits Of A Special POSTBiotic Supplement

Before you load yourself up with fiber and fermented foods, consider this: it takes a LOT of fiber to produce a very special POSTBiotic we'll tell you about in a moment. Yes, those foods should be a part of your diet for their nutrient values and for gut health, but it's a very inefficient way to get a major  postbiotic you need for your health. 

This special POSTBiotic supplement bypasses the old inefficient intestinal fermentation process and goes directly to your lower colon where it’s needed to provide all those digestive and overall health benefits. (Intestinal fermentation is what causes all that gas, bloating, stomach pains, and perhaps even nausea you may experience after eating fibrous foods.)

This special POSTBiotic is a short-chain fatty acid called butyrate.

In one study by Harvard doctors, researchers called butyrate the “optimal” short-chain fatty acid and note that it shows “a higher potency” than other short-chain fatty acids.6 And unlike probiotics, butyrate and other postbiotics supplements stay in your gut for a long time helping to support your health in many ways.

Research suggests butyrate may help:

  • Promote weight loss7
  • Maintain healthy blood sugar levels8
  • Defend against colon cancer 9 (Low-fiber intake is associated with colon cancer)
  • Improve brain function10
  • Soothe anxiety and depression11
  • Improve digestive function, thus reducing gas and bloating12
  • Boost the immune system13
  • Supports gut health
  • And much more

So, why don’t you see butyrate supplements on store shelves or in advertisements?

Well...butyrate is an “unstable molecule” that's destroyed by the digestive process long before it  reaches the colon and cannot be an effective postbiotic supplement on its own. To correct this issue, scientists added 1 glycerol molecule to 3 butyrate molecules to create Tributyrate, a patented POSTBiotic that delivers butyrate directly to the lower colon so that it can go to work immediately.

 

Introducing Viscera-3™ POSTBiotic Formula

Thanks to this major scientific breakthrough, Viscera-3™ is the first and only synergistic gut and immune POSTBiotic formulation to survive digestion and successfully deliver butyrate directly into the lower colon. Viscera-3™ contains clinically proven and patented ingredients to support gut function and overall health. Click here to learn more about our wildly popular Viscera-3™ and place your order today while supplies last!

 

References

 

1- Almario CV, Ballal ML, Chey WD, Nordstrom C, Khanna D, Spiegel B. Burden of Gastrointestinal Symptoms in the United States: Results of a Nationally Representative Survey of Over 71,000 Americans, American Journal of Gastroenterology: November 2018 - Volume 113 - Issue 11 - p 1701-1710 doi: 10.1038/s41395-018-0256-8

2- den Besten, Gijs., et al. The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res. 2013 Sep; 54(9): 2325–2340.

3- Morowitz, M.J., Carlisle, E., Alverdy, J.C. Contributions of Intestinal Bacteria to Nutrition and Metabolism in the Critically Ill. Surg Clin North Am. 2011 Aug; 91(4): 771–785.

4a- Konturek PC, Brzozowski T, Konturek SJ. Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options. J Physiol Pharmacol. 2011 Dec;62(6):591-9. PMID: 22314561.

4b- Pelton R. Beyond Probiotics: Postbiotic Metabolites Regulate Your Health. Natural Medicine Journal. Mar 15, 2019. Accessed Mar 23, 2021. https://www.naturalmedicinejournal.com/blog/beyond-probiotics-postbiotic-metabolites-regulate-your-health

4c- Pelton R. Postbiotic Metabolites: What They Are and Why They Are Important. Essential Formulas. May 19, 2017. Accessed Mar 23, 2021. https://essentialformulas.com/postbiotic-metabolites/#:~:text=Hydrogen%20peroxide%2C%20which%20suppresses%20the%20growth%20of%20candida,postbiotic%20compounds%20that%20have%20yet%20to%20be%20discovered.

5- Zelman KM.  Fiber: How Much Do You Need? Nourish by WebMD. Accessed Feb 17, 2021. https://www.webmd.com/diet/guide/fiber-how-much-do-you-need#1

6- Verma MS, Fink MJ, Salmon GL, Fornelos N,‡ Ohara TE, Ryu SH, Vlamakis H, Xavier RJ, Stappenbeck TS, Whitesides GM. A Common Mechanism Links Activities of Butyrate in the Colon. ACS Chemical Biology 2018 13 (5), 1291-1298. DOI: 10.1021/acschembio.8b00073

7- Gao Z., Yin J., Zhang J., Ward R. E., Martin R. J., Lefevre M., et al. . (2009). Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes 58, 1509–1517. 10.2337/db08-1637

8- Gao Z, Yin J, Zhang J, Ward RE, Martin RJ, Lefevre M, Cefalu WT, Ye J. Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes. 2009 Jul;58(7):1509-17. doi: 10.2337/db08-1637. Epub 2009 Apr 14. PMID: 19366864; PMCID: PMC2699871.

9- Rios-Covian, D, Ruas-Madiedo P, Margolles A, Gueimonde M, de Los Reyes-Gavilan CG, and Salazar N. Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health. Front Microbiol 7: 185, 2016.

10- Megan W. Bourassa,a,b Ishraq Alim. Butyrate, Neuroepigenetics and the Gut Microbiome: Can a High Fiber Diet Improve Brain Health? Neurosci Lett. 2016 Jun 20; 625: 56–63.

11- Messaoudi M, Lalonde R, Violle N, Javelot H, Desor D, Nejdi A, Bisson JF, Rougeot C, Pichelin M, Cazaubiel M, Cazaubiel JM. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. Br J Nutr. 2011 Mar;105(5):755-64. doi: 10.1017/S0007114510004319. Epub 2010 Oct 26. PMID: 20974015.

12- Zaleski, A, Banaszkiewicz A, and Walkowiak J. Butyric acid in irritable bowel syndrome. Prz Gastroenterol 8: 350-353, 2013.

13- Kelly Cushing, David M Alvarado, Matthew A Ciorba. Butyrate and Mucosal Inflammation: New Scientific Evidence Supports Clinical Observation. Clin Transl Gastroenterol. 2015 Aug; 6(8): e108.

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